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US and Brazilian scientists found lower levels of the exercise hormone irisin in the brains of Alzheimer's patients compared with healthy individuals - and say this could pave the way to new treatment.

In Sophie Mackintoshs debut novel, The Water Cure, Lia, Grace and Sky living off the grid with their abusive parents have been raised to fear men. The virtuoso trumpeter, who died last year, will be honored at two venues. After studying with Martha Graham, Ms. Zall went on to create solo works praised for their intense theatricality. Our top photos from the last 24 hours. Britain has recognized its sporting stars in the Queen's New Year's honors list with a knighthood for cricketer Alastair Cook, and awards for Tour de France winner Geraint Thomas, England soccer boss Gareth Southgate and his captain Harry Kane.

A straight man to the outsize personalities who fill the ring, he had a resonant voice that lent a certain gravitas to an enterprise hardly known for it.
AstraZeneca has hired Dr. Jos Baselga, the former chief medical officer at Memorial Sloan Kettering, to lead its cancer research unit.

Israel-based Mobileye, which makes technology for autonomous driving, said on Tuesday it was expanding its business in China with two new partnerships, paving the way for smaller Israeli competitors that could benefit from U.S.-Sino trade tensions.
China's surface water quality improved in 2018, with more samples taken from river and lakes reaching standards fit for human use, the country's environment ministry said on Monday. Indianapolis will face the top-seeded Kansas City Chiefs in the divisional round next weekend.

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